A new Mayo Clinic study published in the New England Journal of Medicine has uncovered that an off-the-shelf, dual-antibody therapy can generate deep and durable responses in extramedullary multiple myeloma — one of the most aggressive and treatment-resistant forms of the disease.
Mayo Clinic
Subtle biological changes linked to Alzheimer’s disease may begin as early as the late 50s — decades before memory loss or other symptoms appear — according to new research from Mayo Clinic. The study, published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, maps when key brain and blood-based changes tend to accelerate […]
A new multicenter study led by Mayo Clinic researchers has established a practical, evidence-based definition for rapidly progressive dementia (RPD), a rare but devastating form of cognitive decline that develops over months instead of years. The findings, published in Neurology, the medical journal of the American Academy of Neurology, may help clinicians recognize and
In a study published in Nature Communications, Mayo Clinic researchers have identified specific DNA-level changes in the brains of people with Alzheimer’s disease (AD). Using advanced biological analysis, the team mapped alterations in the brain’s regulatory landscape that may help explain why Alzheimer’s presents and progresses differently from person to
Alzheimer’s-related brain changes progressed up to 20 times faster in women who also had abnormal levels of a Parkinson’s-related protein, according to a Mayo Clinic study published in JAMA Network Open. The same pattern was not observed in men. The findings suggest that when alpha-synuclein — a protein linked to Parkinson’s disease — accumulates
As rates of obesity, high blood pressure, type 2 diabetes and sleep apnea increase, cases of advanced chronic liver disease and resulting liver scarring or cirrhosis also are rising. Patients often are diagnosed based on symptoms, such as gastrointestinal bleeding, fluid retention or jaundice, which happen when liver disease has progressed to a late stage. […]
“I should stop.” Have you ever said those words to yourself as you scrolled through one disheartening online post after another? This phenomenon is popularly known as doomscrolling. You may wonder: Why is it so difficult to stop doomscrolling once you start? More importantly, what can you do to break free from the negative spiral? […]
To help meet the potentially complex needs of patients after prostate cancer treatment and offer the precision and care necessary in the follow-up journey, Mayo Clinic’s Department of Radiation Oncology developed the PSA Control Tower. This is an intelligent monitoring tool designed to support clinicians in keeping a close, ongoing watch over patients after treatment. […]
In a neurology lab at Mayo Clinic, Dr. Benjamin Brinkmann studies the brain’s electrical rhythms across days, weeks and months — searching for patterns that reveal when seizures are most likely to occur. Working with neuroscientists and clinicians, he combines data from brain waves, vital signs and imaging to develop tools that interpret those signals […]
Sleep data captured with a wearable device could help clinicians better tailor care by identifying patients with chronic obstructive pulmonary disease (COPD) who may need additional support to participate in pulmonary rehabilitation, according to new research published in Mayo Clinic Proceedings: Digital Health. COPD is a long-term lung disease that makes it hard to
DEAR MAYO CLINIC: My husband has been diagnosed with cancer. I know his treatment will be hard on him, and I want to help in any way with his diet. What do you recommend for us? ANSWER: Cancer treatments can take a toll on a person’s body. Your husband’s treatment may cause nausea, changes in appetite, […]
Mayo Clinic researchers collaborated on a new study showing that the drug abemaciclib improves survival for people with high-risk, early-stage breast cancer. In the phase 3 monarchE trial, two years of abemaciclib (Verzenio) plus endocrine therapy reduced the risk of death by 15.8% compared with endocrine therapy alone among patients with a common type […]
Current genetic screening guidelines fail to identify most people with an inherited condition known as familial hypercholesterolemia that can cause dangerously high cholesterol and early heart disease, a Mayo Clinic study found. The condition often passes silently through families for generations. It is highly treatable, yet people who remain undiagnosed are at
Artificial intelligence (AI) applied to abdominal imaging can help predict adults at higher risk of falling as early as middle age, a new Mayo Clinic study shows. The research, published in Mayo Clinic Proceedings: Digital Health, highlights the importance of abdominal muscle quality, a component of core strength, as a key predictor of fall risk in […]
As cancer therapies improve and increasingly achieve cures or recurring periods of remission, preventing and managing damage to organs from cancer treatment has become a top concern. That includes injury to the heart, says Joerg Herrmann, M.D., a cardiologist and the founder and director of the Cardio-Oncology Clinic at Mayo Clinic in Minnesota. As […]
We have a new fitness facility nearby. The pool schedule shows a number of aqua exercise classes. I’d like to try a water fitness class to add variety to my regular fitness routine, but can I really get a good workout in water? ANSWER: Regular exercise provides a wide range of benefits, including weight management, […]
Mayo Clinic researchers have developed a smartwatch-based alert system that signals parents at the earliest signs of a tantrum in children with emotional and behavioral disorders — prompting them to intervene before it intensifies. In a new study published in JAMA Network Open, these alerts helped parents intervene within four seconds and shortened severe tantrums […]
Mayo Clinic researchers have developed a new way to predict whether existing drugs could be repurposed to treat heart failure, one of the world’s most pressing health challenges. By combining advanced computer modeling with real-world patient data, the team has created “virtual clinical trials” that may facilitate the discovery of effective therapies while
Mayo Clinic researchers have developed artificial intelligence (AI) tools that help identify which children with asthma face the highest risk of serious asthma exacerbation and acute respiratory infections. The study, published in the Journal of Allergy and Clinical Immunology, found the tools can detect those risks as early as age 3. The work is […]
At the heart of World Health Expo 2026 (formerly Arab Health), one of the world’s foremost healthcare exhibitions, Saudi German Health (SGH) and Mayo Clinic convened a senior leadership session to examine how global medical expertise and regional healthcare delivery models can work together to strengthen healthcare systems and improve patient outcomes across the region.





























